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Clinical Trials

RECRUITING
Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Lupus (SIRIUS-SLE 2)
The trial will assess efficacy, safety and tolerability of ianalumab compared to placebo, given as monthly subcutaneous (s.c.) injection on top of sta...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Anniston, Alabama, United States
📍 Irvine, California, United States
📍 La Palma, California, United States
📍 Miami, Florida, United States
87 more locations available...
RECRUITING
Study on DS-7011a in Patients With Lupus
Systemic lupus erythematosus (SLE) is a systemic chronic autoimmune disease characterized by autoantibody production, inflammation, and tissue damage ...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Anniston, Alabama, United States
📍 North Little Rock, Arkansas, United States
📍 North Miami Beach, Florida, United States
📍 Tamarac, Florida, United States
8 more locations available...
RECRUITING
Study of Edecesertib in Patients With Cutaneous Lupus Erythematosus (CLE)
The goal of this clinical study is to test how edecesertib (formerly known as GS-5718) can be useful in treating Cutaneous Lupus Erythematosus (CLE) i...
Conditions:
Cutaneous Lupus Erythematosus (CLE)
Locations:
📍 Fremont, California, United States
📍 La Jolla, California, United States
📍 Upland, California, United States
📍 Aurora, Colorado, United States
26 more locations available...
RECRUITING
Study on Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)
The purpose of this study is to assess the efficacy and safety of zetomipzomib (30 mg or 60 mg) compared with placebo in achieving renal response afte...
Conditions:
Lupus Nephritis
Locations:
📍 Huntsville, Alabama, United States
📍 Surprise, Arizona, United States
📍 Los Alamitos, California, United States
📍 Torrance, California, United States
158 more locations available...
RECRUITING
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
The study is a 1-year 2-part double-blinded placebo controlled 2-arm clinical trial. Treatment arms are (1) MMF dosed as per body-surface area (MMFBSA...
Conditions:
Lupus Nephritis
Locations:
📍 Chicago, Illinois, United States
📍 Hackensack, New Jersey, United States
📍 New York, New York, United States
📍 New York, New York, United States
3 more locations available...
RECRUITING
A Study on the Safety, Tolerance, Drug Levels and Drug Effects of BMS-986326 in Adult Patients With Different Forms of Lupus
The purpose of this study is to assess safety, drug levels and drug effects on cells and organs of the body, after receiving multiple increasing doses...
Conditions:
Lupus
Locations:
📍 San Diego, California, United States
📍 Clearwater, Florida, United States
📍 Tampa, Florida, United States
📍 Lawrenceville, Georgia, United States
17 more locations available...
RECRUITING
Study on CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Patients With Severe, Refractory Autoimmune Diseases
The purpose of this study is to establish the tolerability, preliminary efficacy, and pharmacokinetics of CC-97540 in patients with severe, refractory...
Conditions:
Systemic Lupus Erythematosus Idiopathic Inflammatory Myopathy Systemic Sclerosis
Locations:
📍 Aurora, Colorado, United States
📍 Denver, Colorado, United States
📍 New Haven, Connecticut, United States
📍 Jacksonville, Florida, United States
50 more locations available...
RECRUITING
Study on IMPT-514 in Active Refractory Lupus (SLE)
This is a Phase 1/2, multi-center, open-label study evaluating the safety and efficacy of IMPT-514, a bispecific chimeric antigen receptor (CAR) targe...
Conditions:
Systemic Lupus Erythematosus Lupus Nephritis
Locations:
📍 Los Angeles, California, United States
📍 San Francisco, California, United States
📍 Iowa City, Iowa, United States
📍 Detroit, Michigan, United States
2 more locations available...
RECRUITING
Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Lupus
Study Description: Systemic lupus erythematosus (SLE) occurs predominantly in women and is driven by type I interferon dysregulation and neutrophil h...
Conditions:
Systemic Lupus Erythematosus (Sle)
Locations:
📍 Bethesda, Maryland, United States
RECRUITING
Maternal Autoimmune Disease Research Alliance (MADRA) Registry
This multi-site registry, centered at Duke University, will enroll pregnant women with autoimmune and rheumatologic diseases. The main goal of MADRA ...
Conditions:
Autoimmune Diseases Pregnancy Related Systemic Lupus Erythematosus Cutaneous Lupus
3 more conditions available...
Locations:
📍 Durham, North Carolina, United States
RECRUITING
Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Lupus (SIRIUS-SLE 1)
The trial will assess efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneous (...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Burbank, California, United States
📍 La Jolla, California, United States
📍 Los Angeles, California, United States
📍 Simi Valley, California, United States
122 more locations available...
RECRUITING
Intervention to Improve Communication and Medication Adherence in Lupus
CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE). ...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Durham, North Carolina, United States
RECRUITING
A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Lupus
The goal of this clinical trial is to see how well cenerimod reduces symptoms of Lupus in adult patients with moderate to severe symptoms. The main qu...
Conditions:
Lupus Erythematosus, Systemic
Locations:
📍 Fullerton, California, United States
📍 Aurora, Colorado, United States
📍 Boca Raton, Florida, United States
📍 Clearwater, Florida, United States
114 more locations available...
RECRUITING
Cutaneous Lupus Registry
Approximately 1.4 million individuals in the United States have systemic lupus erythematosus, and about 85% of these individuals develop skin lesions ...
Conditions:
Lupus Erythematosus
Locations:
📍 Dallas, Texas, United States
RECRUITING
Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE
The purpose of this study is to assess the safety, tolerability and efficacy of emapalumab in children and adults with macrophage activation syndrome ...
Conditions:
Macrophage Activation Syndrome Secondary Hemophagocytic Lymphohistiocytosis Still Disease Systemic Lupus Erythematosus
3 more conditions available...
Locations:
📍 Birmingham, Alabama, United States
📍 Los Angeles, California, United States
📍 Gainesville, Florida, United States
📍 Atlanta, Georgia, United States
45 more locations available...

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