Rheumatology Patient Registry and Biorepository

RECRUITING

I'm interested ...!!

To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.

Conditions:

Rheumatic Diseases Adult Onset Still Disease Ankylosing Spondylitis Psoriatic Arthritis Reactive Arthritis Antiphospholipid Syndrome Systemic Lupus Erythematosus Behcet Disease Dermatomyositis Polymyositis Giant Cell Arteritis Lyme Disease Mixed Connective Tissue Disease Polymyalgia Rheumatica Rheumatoid Arthritis Sarcoidosis Systemic Sclerosis Scleroderma Sjogren's Syndrome Undifferentiated Connective Tissue Diseases

More conditions available...

Study Start (Actual) 2020-08-04

Primary Completion (Estimated) 2030-06-01

Study Completion (Estimated) 2030-06-01

Enrollment (Estimated) 5000

Study Type OBSERVATIONAL

Phase N/A

Locations:

📍 New Haven, Connecticut, United States

Eligibility Criteria

Description

Inclusion Criteria for Rheumatology Patients:
* Patients ≥18 years old with a diagnosis of a rheumatic autoimmune disease including, but not limited to: adult onset Still's disease, ankylosing spondylitis, antiphospholipid syndrome, Behcet's disease, dermatomyositis, giant cell arteritis, mixed connective tissue disease, polymyalgia rheumatica, polymyositis, psoriatic arthritis, reactive arthritis, rheumatoid arthritis, sarcoidosis, scleroderma, Sjogren's syndrome, systemic lupus erythematosus, undifferentiated connective tissue disease and vasculitis.
* Receiving clinical care at Yale Rheumatology clinics
Exclusion Criteria for Rheumatology Patients:
* Unable to provide informed consent
* No patients will be excluded based on gender or ethnicity or pregnancy status.
* Women who are currently pregnant will need to wait to donate a skin biopsy until after they deliver.
* Patients allergic to lidocaine or epinephrine or have a history of impaired wound healing will not be able to donate a skin biopsy.
Inclusion Criteria for Healthy Volunteers:
* Age ≥ 18 years old
* No chronic skin conditions
* No diagnosis of a rheumatic autoimmune disease (e.g., lupus, rheumatoid arthritis)
* Normal BMI
Exclusion Criteria for Healthy Volunteers:
* Unable to provide informed consent.
* Currently pregnant or nursing unless the study goal is to study pregnant or nursing woman.
* Allergies to lidocaine or epinephrine (skin biopsies).
* A history of impaired wound healing (skin biopsies).

Ages Eligible for Study: 18 Years to 99 Years (ADULT, OLDER_ADULT)

Sexes Eligible for Study: ALL

Accepts Healthy Volunteers: Yes

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted2020-05-20
First Submitted that Met QC Criteria2020-05-20
First Posted2020-05-26

Study Record Updates

Last Update Submitted that Met QC Criteria2023-12-21
Last Update Posted2024-01-02
Last Verified2023-12