Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)

RECRUITING

I'm interested ...!!

The mission of this project is to increase the detection of Primary Aldosteronism (PA), the most common cause of secondary hypertension, which can either be cured surgically or treated with targeted medications.

Conditions:

Primary Aldosteronism

Study Start (Actual) 2023-05-02

Primary Completion (Estimated) 2025-03-30

Study Completion (Estimated) 2025-08-29

Enrollment (Estimated) 50

Study Type OBSERVATIONAL

Phase N/A

Locations:

📍 Cleveland, Ohio, United States

Eligibility Criteria

Description

Inclusion Criteria:

* Consent to participate in the study
* Participants limited to subjects in the CCF
* Age between and inclusive of 18 and 65 years of age
* No gender exclusion
* Patients diagnosed with Essential Hypertension by ICD-10 code on at least two occasions in the previous six months, even if not on medications for hypertension
* Patients on a single anti-hypertensive medication for at least six months with the diagnosis of hypertension

Exclusion Criteria:

* Those on a mineralocorticoid antagonist therapy (spironolactone, eplerenone)
* Those with a documented diagnosis of primary aldosteronism or primary hyperaldosteronism
* Those with a diagnosis of secondary hyperaldosteronism
* Those with a diagnosis of heart failure, renal artery stenosis, cirrhosis, ascites, cor pulmonale.
* Pregnancy status (verbal)

Ages Eligible for Study: 18 Years to 65 Years (ADULT, OLDER_ADULT)

Sexes Eligible for Study: ALL

Accepts Healthy Volunteers: No

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted2023-02-24
First Submitted that Met QC Criteria2023-02-24
First Posted2023-03-07

Study Record Updates

Last Update Submitted that Met QC Criteria2024-05-06
Last Update Posted2024-05-07
Last Verified2024-05